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2017

Evaluating BRCA1 haploinsufficiency as a putative target for the prevention of BRCA1-associated cancer


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GRANTEE
Joanne Kotsopoulos, Ph.D.
POSITION
Associate Professor, University of Toronto, Toronto, Canada
INSTITUTION
Women’s College Hospital

The laboratory of Dr. Kotsopoulos is testing if increasing the amount of normal BRCA1 in patients with BRCA1 mutations can prevent cancer. To do this they are developing a cell-based test to screen for drugs, small molecules or natural compounds that can increase BRCA1 protein levels. They will then validate what they find in the screen on a variety of pre-clinical models that have only one normal copy of BRCA1.

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Phone: 1-844-437-4791
Donate at Southwestern Medical Foundation/CPI
CPI is a 501(c)(3) organization 47-3425850 

 

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