Blogs & Interviews

Blogs & Interviews

A high-throughput approach to identify BRCA1-downregulating compounds to enhance PARP inhibitor sensitivity

A CPI grant funded Dr. Kotsopoulos at the University of Toronto, Toronto, Canada for Evaluating BRCA1 haploinsufficiency as a putative target for the prevention of BRCA1-associated cancer. She and her collaborators developed a cell-based test to...
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In Memory of Dr. Charis Eng

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Li Fraumeni Syndrome and one family’s harrowing experience with this deadly disease

Li Fraumeni (LF) is a hereditary cancer syndrome due to deleterious inherited mutations in the TP53 gene that increases the risk for developing a wide range of cancers, mostly sarcomas, breast cancers, brain tumors, and leukemias. In the Wall...
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Expert Interview with Alan Venook, MD, on colorectal cancer and the promise of immunotherapy for prevention and treatment

Posted February 9, 2023 - Dr. Alan Venook is a nationally renowned expert in gastrointestinal cancers such as colorectal cancer (CRC) and liver cancer. He is based at University of California, San Francisco (UCSF) and holds the Madden Family...
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Expert Interview with David Reese, MD, on cancer prevention and precision medicine

Posted June 23, 2022 - Dr. David Reese is Executive Vice President, Research and Development (R&D) at Amgen. In his current role, he oversees Discovery Research, Global Development, Global Regulatory Affairs and Safety, and Global Medical....
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Expert Interview with Ray Deshaies, PhD, on drug development and cancer therapeutics

Posted on March 14, 2022 - Dr. Ray Deshaies is Senior Vice President of Global Research at Amgen and a Visiting Associate at the California Institute of Technology (Caltech).  Prior to joining Amgen, Dr. Deshaies received his BS in...
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